Nephrology Critical Care

John S, Eckardt KU. Renal replacement in the ICU. Chest  2007;132:1379-88. Explains the various forms of hemodialysis, ultrafiltration, and hemofiltration.
PMID:  17934125
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Vinsonneau C, Camus C, Combes A, et al. Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome.  Lancet  2006 ; 368 :379-85.  Like previous RCTs addressing this issue, this multicenter study of 360 ICU patients found no advantage to continuous venovenous dialysis in terms of 60-day survival.  A limitation of the study is that the delivered dialysis dose may have been suboptimal for both arms.
PMID:  16876666
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Palevsky PM, Zhang JH, O’Connor TZ, et al. Intensity of renal support in critically ill patients with acute kidney injury.  N Engl J Med  2008; 359:7-20. The ATN Study included 1,124 patients with acute kidney failure requiring dialysis plus failure of 1 other organ system or sepsis. Unlike previous studies, more intensive renal replacement therapy did not improve outcomes, regardless of whether therapy was intermittent or continuous. Of note, the less intensive replacement group still received standard amounts of therapy and required ultrafiltration more often for volume control.
PMID:  18492867
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Brochard L, Abroug F, Brenner M, et al. for the ATS/ERS/ESICM/SCCM/SRLF Ad Hoc Committee on Acute Renal Failure.  Management of acute renal failure in the ICU patient:  an international consensus conference in intensive care medicine.  Am J Respir Crit Care Med 2010;181:1128-55.  Seeks to answer clinical questions regarding the identification, prevention, and management of acute kidney insufficiency in the intensive care setting, including a discussion of contrast-induced nephropathy.
PMID: 20460549