Bone Marrow Transplantation

Kotloff RM, Ahya VN, Crawford SW et al. Pulmonary complications of solid organ and hematopoietic stem cell transplantation. Am J Respir Crit Care Med 2004; 170:22-48. A State of Art article that provides an excellent overview of the complications of solid organ and hematopoietic stem cell transplantation. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15070821
Segal BH, Walsh TJ, Current approaches to diagnosis and treatment of invasive aspergillosis.  Am J Respir Crit Care Med. 2006; 173:707-17.  Excellent review of aspergillosis in bone marrow transplant patients and other immune-compromised patients, including diagnosis, antifungal therapy, and immune augmentation strategies. http://www.ncbi.nlm.nih.gov/pubmed/16387806?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Feinstein MB, Mokhtari M, Ferreiro R, et al. Fiberoptic bronchoscopy in allogeneic bone marrow transplantation. Chest 2001;120:1094-1100. Case series of 61 patients undergoing 76 bronchs in the late 1990s found FOB was diagnostic in 42% of patients and directly changed management in 32% of patients. Infection was the most common diagnosis (42% of patients) followed by diffuse alveolar hemorrhage (8% of bronchs). CMV was the most common infection (30%), a substantially lower proportion than in series from the 1980s. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11591544