HIV and Pulmonary Disease

Gagnon S, Boota AM, Fischl MA, et al. Corticosteroids as adjunctive therapy for severe PCP in AIDS. N Engl J Med 1990;323:1444-50. One of three studies published in the same year establishing the efficacy of steroids in severe PCP in patients with AIDS. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2233916

Hirschtick RE, Glassroth J, Jordan MC, et al. Bacterial pneumonia in persons infected with the human immunodeficiency virus. Pulmonary Complications of HIV Infection Study Group. N Engl J Med 1995;333:845-51. Part of the landmark PCHIS study, this is the first and best prospective study of CAP in HIV-infected patients. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7651475

Huang L, Quartin A, Jones D, et al. Intensive care of patients with HIV infection.  N Engl J Med 2006:355;173-181. This review provides a particularly nice discussion of the risks and benefits of antiretroviral medications in critically-ill patients. http://www.ncbi.nlm.nih.gov/pubmed/16837681?ordinalpos=236&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum