ATS Reading List

Cough

Gibson P, Wang G, McGarvey L, et al. Treatment of unexplained chronic cough: CHEST guideline and expert panel report. Chest; 2016:149:27-44. This new guideline aims to clarify the best evidence for assessment and treatment of unexplained chronic cough (UCC). It highlights the significant morbidity of the condition and the limited evidence available to guide management.
PMID: 26426314
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Vertigan AE, Kapela SL, Ryan NM, et al. Pregabalin and speech pathology combination therapy for refractory chronic cough: a randomized controlled trial. CHEST. 2016; 149:639-48. This RCT of speech therapy with or without pregabalin in 40 patients with chronic refractory cough found improved cough severity, frequency, and quality of life in both groups. However cough severity and quality of life were significantly better in the combined treatment group. The small sample size and stringent eligibility criteria may limit the generalizability of these findings.
PMID: 26447687

Last Reviewed: June 2017